Phthalic anhydride, the anhydrous form of the acid, gave no evidence of carcinogenicity in longterm feeding studies in rats and mice. Our network of locallybased reporters publish weekly price assessments for spot and contract, depending on the region. Learn definitions, uses, and phrases with phthalic. Phthalates are a group of industrial compounds produced by the esterification of phthalic anhydride with an alcohol e. It is presently obtained by catalytic oxidation of ortho xylene or naphthalene. The icis phthalic anhydride reports will keep you informed and uptodate with market movements in asia, europe and the us. Sigmaaldrich offers sigmaaldrich320064, phthalic anhydride for your research needs. Phthalic acid is used mainly in the form of the anhydride to produce other chemicals such as dyes, perfumes, saccharin, phthalates and many other useful products. Is phthalic anhydride is soluble in methanol answers. The first reaction step results in the formation of a monoester, which is subsequently converted to a diester in a second reaction step. Unlike most such conversions this happens with ease. Undergoes exothmeric nitration with fuming nitric acidsulfuric acid and may give mixtures of the potentially explosive phthaloyl nitrates or nitrites or their nitro derivatives chem. Phthalic anhydride is also used as an intermediate in the production of pigments and dyes, agricultural, pharmaceutical, and several other chemical products. Phthalic anhydride pa is a white crystalline compound used to manufacture plasticizers, pigments, dyes and resins.
However, the revised idlh for phthalic anhydride is 60 mgm 3 i. The primary use of phthalic anhydride pa is as a chemical intermediate in the production of plasticizers from polyvinyl chloride pvc. This white solid is an important industrial chemical. Our pa plant is a manufacturing plant which opened for the first time in the republic of korea. Undergoes exothmeric nitration with fuming nitric acid sulfuric acid and may give mixtures of the potentially explosive phthaloyl nitrates or nitrites or their nitro derivatives chem. Us2105911a us54507531a us2105911a us 2105911 a us2105911 a us 2105911a us 54507531 a us54507531 a us 54507531a us 2105911 a us2105911 a us 2105911a authority us united states prior art keywords phthalic anhydride sulfuric acid catalytic impure distillate prior art date 19260121 legal status the legal status is an assumption and is not a legal.
Phthalic anhydride is a white crystalline solid that is the commercial form of phthalic acid. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. Pan is a principal commercial form of phthalic acid, discovered in 1836. This phthalic anhydride will be used in further synthesis to make phenolphthalein and phthalimide precursor to anthranilic acid. Structure, properties, spectra, suppliers and links for. Find product specific information including uses, price, cas, msds, protocols and references. Phthalic anhydride is a white lustrous needles solid that is slightly soluble in water. Phthalic anhydride is used to manufacture materials such as artificial resins. Phthalic is contained in 2 matches in merriamwebster dictionary. Phthalic anhydride can also be prepared from phthalic acid. Phthalic anhydride is an important starting product in the manufacture of various phthalicacid derivatives, including esters, phthalimide, and phthalonitrile. Phthalic anhydride manufacturer in india thirumalai.
It is more severely irritating in the presence of water, due to the pronounced effects of the phthalic acid which is formed. Code of federal regulations title 49 section 172 shipping regulations and proper shipping name. Phthalic acid is an aromatic dicarboxylic acid, with formula c6h4cooh2. This colorless solid is an important industrial chemical, especially for the largescale production of plasticizers for plastics. Phthalic anhydride is usually used as a chemical median for the production of plastics from vinyl chloride. Phthalic anhydride is an organic compound known by the molecular formula c6h4co2o. Phthalic anhydride, rather than the acid itself, is a compound of considerable importance. The annual production of phthalic anhydride exceeded 1,000,000 metric tons in the late 20th century. Phthalic anhydride is the cyclic dicarboxylic anhydride that is the anhydride of phthalic acid. Opa did not cause mutations in bacterial tests including ames, but a mutagenic effect was seen in fruit flies ref. Synthesis of anthranilic acid and phthalic anhydride ligand and their metal complexes saleem raza 1, yousaf iqbal, iqbal hussian2, muslim raza1, syed uzair ali shah 3, ajmal khan, raheela taj 1 and abdur rauf 1institute of chemical sciences, university of peshawar, peshawar, pakistan.
Usdot 2008 emergency response guidebook initial response information. Basf has been producing pa for over 140 years and researching pa catalysts for more than 120 years. Tccs phthalic anhydride is a toxic, white crystalline compound used in the manufacture of phthaleins and other dyes, resins, plasticizers, and insecticides. Phthalic anhydride is slightly soluble in methanol. Phthalic acid, when found in tissues or biofluids arises from exposure to these phthalate products.
Phthalic anhydride definition is a crystalline cyclic acid anhydride c8h4o3 used especially in making alkyd resins. Phthalic acid is an aromatic dicarboxylic acid, with formula c 6 h 4 co 2 h 2. Synthesis of anthranilic acid and phthalic anhydride ligand. Phthalic anhydride is a principal commercial form of phthalic acid. Phthalic anhydride definition of phthalic anhydride at. How to make phthalic acid and phthalic anhydride youtube. Market news and analysis includes an overview, regional. Others have collected phthalic anhydride on glass fiber filters and extracted with dilute aqueous sodium hydroxide ref. Thermal decomposition of ophthalic acid 1,2benzenedicarboxylic or simply phthalic acid starting around 200c leads to the formation of phthalic anhydride. Phthalic anhydride reacts violently with cuo at elevated temperatures park, changman, richard j.
It will, for example, react readily with alcohols on warming, yielding initially the halfesters of phthalic acid, the alkyl hydrogen phthalates xii. About 1% of these are appliance paint, 0% are building coating, and 35% are pharmaceutical intermediates. The largest markets for phthalic anhydride are phthalate plasticizers, unsaturated polyester resins, and alkyd resins for surface coatings. Prolonged or repeated exposure also may cause dermatitis.
In this case, phthalic anhydride will actually react with its solvent. Molecular formula of phthalic anhydride e c 8 h 4 o 3. The source is also providing more information like the publication year, authors and more. Phthalic definition, of or derived from phthalic acid. Phthalic anhydride containing materials are used in coatings applications for home appliances, automobiles, medical devices and furniture. Exposure routes inhalation, ingestion, skin andor eye contact.
Cdc niosh pocket guide to chemical hazards phthalic anhydride. In this video we will be extracting dehp from vinyl gloves, and then cleaving the ester bonds to form alcohols and phthalic acid. Jan 26, 2015 this method was borrowed from both youtuber users nurdrage and uc235. It was the first anhydride of a dicarboxylic acid to be used commercially and is comparable in its importance to acetic acid.
This page contains information on the chemical phthalic anhydride including. Phthalic anhydride containing materials are used in coatings applications for home. Phthalic anhydride is the organic compound with the formula c6h4co2o. Phthalic anhydride article about phthalic anhydride by the. Phthalic anhydride is used to make polymeric resins called alkyd resins, which are used as coatings, especially for appliances and automobiles. Unlike most such conversions this happens with ease due to the formation of a 5membered ring. Phthalic anhydride is converted to phthalic acid in the presence of water. It was the first anhydride of a dicarboxylic acid to be used commercially. Conversion of phthalic acid to phthalic anhydride august 10, 20 by magpie a.
Phthalic anhydride is the organic compound with the formula c 6 h 4 co 2 o. Synthesis of anthranilic acid and phthalic anhydride. This colorless solid is an important industrial chemical, especially for the largescale production of. I make phthalic anhydride from phthalic acid by heating. Manufacturer and substance identification thirumalai chemicals limited. It is known as an adaptable intermediate in chemical processes because it is bifunctional and readily available. It is an isomer of isophthalic acid and terephthalic acid. This method was borrowed from both youtuber users nurdrage and uc235. Further esterification in the presence of sulphuric acid gives rise to the dialkyl phthalates. Pan is a versatile intermediate in organic chemistry. Concentration information is not available for this spectrum and, therefore, molar absorptivity values cannot be derived. Find more compounds similar to phthalic anhydride note. Phthalic anhydride is an important starting product in the manufacture of various phthalic acid derivatives, including esters, phthalimide, and phthalonitrile. A wide variety of phthalic anhydride options are available to you.
Synthesis of anthranilic acid and phthalic anhydride ligand and their metal complexes saleem raza 1, yousaf iqbal, iqbal hussian2, muslim raza1, syed uzair ali shah 3, ajmal khan, raheela taj 1 and abdur rauf 1institute of chemical sciences, university of. Introduction phthalic acid can be converted to phthalic anhydride by heating the acid above 180c. Urine samples were also subjected to acid, alkaline. Phthalic anhydride market size, share, trends, global. Because both these methods convert the collected phthalic anhydride to, and analyze as, phthalic acid, they are susceptible to positive interference from any phthalic acid originally present in the air. The condensation of phthalic anhydride with phenols is used to obtain dyes, such as phenolphthalein. Phthalic anhydride is a versatile intermediate in organic chemistry, in part because it is bifunctional and readily available. Oct 31, 2017 i make phthalic anhydride from phthalic acid by heating. Conversion of phthalic acid to phthalic anhydride sciencemadness. Melt of phthalic anhydride containing a small amount of azeotroping agent is maintained at a temperature of from 160 to 200c. Basf provides phthalic anhydride pa catalysts for the production of phthalic anhydride from the oxidation of oxylene and naphthalenemixed feed.
Cdc niosh pocket guide to chemical hazards phthalic. Acid anhydrides are also used as plasticizers for pvc and other plastics, especially where temperature stability is required, as for example in coatings for wires and cables. Phthalic anhydride definition of phthalic anhydride by. Phthalic acid and derivatives lorz major reference works. Making phthalic anhydride from phthalic acid youtube. Phthalic anhydride is a direct but delayed irritant of the skin. Phthalic acid, colourless, crystalline organic compound ordinarily produced and sold in the form of its anhydride. The phthalic anhydride plant is an integral part of the iso 9001.
Phthalic anhydride article about phthalic anhydride by. The most important reaction of pan is with alcohols or diols to give esters or polyesters. Synthesis of fluorescein from resorcinol and phthalic anhydride. Phthalic acid anhydride, 1,3isobenxofurandione, 1,2 benzene carboxylic acid anhydride. Phthalic anhydride pa is used as the major ingredient in the manufacture of plasticizers, unsaturated polyester resin, paint and others. Igpl is one of the largest single location producers of phthalic anhydride pan of international standards. Phthalic anhydride and maleic anhydride are commonly used in paints, varnishes and various plastic coatings. Phthalic anhydride an overview sciencedirect topics. Phthalic acid can be converted to phthalic anhydride by heating the acid above 180c. Rabbit sperm motility was inhibited by the potassium salt.
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